This cold February weather has encouraged us to stay indoors more and focus on some interesting dementia research studies along with films about early-onset Alzheimer’s. The current movie ‘Still Alice’ has piqued our interest in learning more about this rare form of early-onset Alzheimer’s.

I recently saw an HBO Alzheimer’s Project video about the DeMoe family. Five of the six brothers and sisters carry one of the genetic mutations that cause the inherited, early-onset Alzheimer's disease. In the video, I observed the emotional toll it has taken on the one sibling who did not inherit the gene. The video is available on the Alzheimer’s Association website. According to the website, the DeMoe family partnered with “…the University of Pittsburgh doctors to understand the course of early-onset Alzheimer's.”

Just as we learned about Seth Rogen’s mother-in-law being diagnosed with early-onset or familial Alzheimer’s, we have also learned about the DeMoe family. What we learn and how we are inspired gives us purpose. If the DeMoe family has become a motivation for researchers, they will surely inspire you to learn more about this rare form of Alzheimer’s.

Research Headlines of February 2015

Mild Cognitive Impairment, Diabetes and Dementia Risk

A meta-analysis that covered 62 studies was carried out by the University College London (UCL). The study included data regarding individuals who had been diagnosed with Mild Cognitive Impairment (MCI). The study found that those who had diabetes and MCI were 65-percent more likely to “progress to dementia.” Dr Claudia Cooper was the lead author of the study. Researchers at the University College London (UCL) published their study's findings in the American Journal of Psychiatry. An article about the study was also published and shared by Neuroscience News.

Molecule Might Slow Accumulation of Protein Clumps in the Brain

Samuel Cohen, from the University of Cambridge, led a study that identified how a molecule might delay and slow down the accumulation of protein clumps in the brain. The study was published in the journal Nature Structural & Molecular Biology. An article about this study was written by science correspondent Hannah Devlin and was published in The Guardian Feb. 16, 2015. The article was retrieved Feb. 25, 2015, from

Anxiety, Length of Telomeres and Cell Ageing

A recent study suggests anxiety contributes to the shortening of telomeres in individuals with anxiety disorders. Shorter telomeres contribute to cellular ageing. The first lead author of the study is Josine Verhoeven, from the VU University Medical Center, in Amsterdam, the Netherlands. The study was published Feb. 5, 2015, in the British Journal of Psychiatry, and retrieved Feb. 25, 2015, from

Florida State University: Blueberries Help Improve Borderline High Blood Pressure

A recent study suggests that eating blueberries may help improve "borderline high blood pressure" in some middle-aged women. The lead author of the study is Sarah Johnson, a researcher at Florida State University in Tallahassee, Florida. As many already know, a healthy heart provides for a healthy brain. An article about the blueberry and blood pressure study was written by Linda Thrasybule and was posted by Reuters Health, and retrieved Feb. 8, 2015, from

We hope this information about early-onset Alzheimer’s along with current research has been helpful. If you would like to know about Senior Helpers of Orlando’s  home health services, and inquire about our Alzheimer’s and Dementia Senior Gems® program, give us a call at 407-628-4357. Senior Helpers of Orlando provides home health services and dementia care in Orange, Osceola and Seminole counties.


Ana P. DeLane

Senior Helpers of Orlando Team Member

Resources about early-onset Alzheimer’s:

Causes of Early Onset Including Genetics; Younger/Early Onset Alzheimer's & Dementia; Alzheimer’s Association; retrieved Feb. 24, 2015, from

DeMoe Family; retrieved link from Alzheimer’s Association, Feb. 24, 2015, from

Familial Alzheimer’s Disease; About Genes and Alzheimer’s Disease; Fact Sheet; Alzheimer’s Association; retrieved Feb. 24, 2015, from

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